PAPPA2 Antibody - N-terminal region: HRP (ARP42555_P050-HRP)

• Gene Name:

  Pappalysin 2

• Gene Aliases:

  PAPPE, PLAC3, PAPP-E, PAPP-A2

• Gene ID:

  60676

• Swiss Prot:

  A9Z1Y8

• Accession Number:

  NP_068755

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Guinea Pig

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human PAPPA2

• Target:

  PAPPA2 is a metalloproteinase which specifically cleaves IGFBP-5. It shows limited proteolysis toward IGFBP-3.

• Partner Proteins:

  ZNF512B; SMAD4; ATF7IP; IGFBP5; IGFBP3

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  PAPPA2 is strongly supported by BioGPS gene expression data to be expressed in HEK293T

• Concentration:

  0.5 mg/mL

• Homology:

  Guinea Pig: 85%; Human: 100%; Rat: 86%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  92kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  827

• NCBI Gene Symbol:

  PAPPA2

• Protein Name:

  Pappalysin-2

• Nucleotide Accession Number:

  NM_021936