SRSF10 Antibody - N-terminal region: FITC (ARP40671_P050-FITC)

• Gene Name:

  Serine and arginine rich splicing factor 10

• Gene Aliases:

  NSSR, TASR, SRp38, TASR1, TASR2, FUSIP1, FUSIP2, SFRS13, SRrp40, SFRS13A, PPP1R149

• Gene ID:

  10772

• Swiss Prot:

  O75494

• Accession Number:

  NP_473357

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human FUSIP1

• Target:

  This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein interacts with the oncoprotein TLS, and abrogates the influence of TLS on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4, 9, 14, 18, and 20. Alternative splicing results in multiple transcript variants.

• Partner Proteins:

  STAU1; WWOX; SUZ12; EED; RNF2; EZH2; HECW2; TRA2B; SRSF4; SRSF1; CSNK2A1; EIF4A3; MAGOH; PAXIP1; BARD1; SAP18; VTN; TCOF1; SRSF6; S100A9; PRKDC; NHP2L1; NFIA; SEPT2; MSH2; IK; EPRS; DHX15; BCAS2; TRIM55; THOC6; ZNF687; SMU1; TRMT112; TRA2A; PHGDH; NCSTN

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 93%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  31kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  262

• NCBI Gene Symbol:

  SRSF10

• Protein Name:

  Serine/arginine-rich splicing factor 10

• Nucleotide Accession Number:

  NM_054016