TRIM8 Antibody - N-terminal region: FITC (ARP39655_P050-FITC)

• Gene Name:

  Tripartite motif containing 8

• Gene Aliases:

  GERP, RNF27

• Gene ID:

  81603

• Swiss Prot:

  Q9BZR9

• Accession Number:

  NP_112174

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM8

• Target:

  TRIM8 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.

• Partner Proteins:

  BRAP; TRIM25; PCGF5; MSL2; RNF141; TRIM2; USP7; TP53; CCNH; OTUB2; USP21; USP39; USP2; TNFAIP3; UBE2D2; TRIM47; TRIM15; TRIM8; RAD18; TRIM39; RNF111; RC3H2; RNF138; RNF181; RCHY1; RNF41; TRIM43; UHRF2; TRIM9; RNF7; TRIM24; RNF113A; MKRN3; TRAF5; TRIM21; S

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  IHC, WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  61kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  551

• NCBI Gene Symbol:

  TRIM8

• Protein Name:

  Probable E3 ubiquitin-protein ligase TRIM8

• Nucleotide Accession Number:

  NM_030912