UBTF Antibody - C-terminal region: HRP (ARP39068_P050-HRP)

• Gene Name:

  Upstream binding transcription factor

• Gene Aliases:

  UBF, UBF1, UBF2, UBF-1, CONDBA, NOR-90

• Gene ID:

  7343

• Swiss Prot:

  P17480

• Accession Number:

  XP_006722124

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Yeast, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C-terminal region of Human UBF1

• Target:

  This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.

• Partner Proteins:

  UBC; MDM2; RNF2; Dlg4; ESR1; CDK4; CDK2; CCNE1; CCND1; WDR70; YEATS4; RB1; GRK5; KAT5; SIRT7; POLR1A; MYBBP1A; HDAC1; RUNX2; SUMO2; SMARCA5; MAPK3; MAPK1; SUMO1; PIK3CA; IRS1; TAF1D; tat; MCRS1; TLE1; ACTN4; POLR1E; CHGB; SMURF1; TCOF1; MAD1L1; ZMYM2; SER

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 86%; Rabbit: 93%; Rat: 93%; Yeast: 86%; Zebrafish: 79%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  84kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  764

• NCBI Gene Symbol:

  UBTF

• Protein Name:

  Nucleolar transcription factor 1