RAD54B Antibody - middle region : HRP (ARP36408_P050-HRP)

• Gene Name:

  RAD54 homolog B (S. cerevisiae)

• Gene Aliases:

  RDH54

• Gene ID:

  25788

• Swiss Prot:

  Q9Y620

• Accession Number:

  NP_036547

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human RAD54B

• Target:

  RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.

• Partner Proteins:

  TCEANC; ATPAF2; ANKRD36BP1; ENKD1; MYO15B; GMCL1; RAD54B; CDC23; SUMO1; PRKAA1; FUS; HECW2; PSMA1; RAD51; NUDT18; NIF3L1; TCEB3; COPS6; SUMO2; UBC; WRN; ZNF580; LNX1; TRAPPC6A; RIBC2; CCDC33; UBE2I; GORASP2; DYRK2; DMC1; CSNK1E; CD2BP2

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  IHC, WB

• Purification:

  Affinity Purified

• Sample Type:

  RAD54B is supported by BioGPS gene expression data to be expressed in HeLa

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 92%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  103kDa

• References & Citations:

  Brys, M., (2007) Pol J Pathol 58 (1), 3-6

• Shipping Conditions:

  Wet Ice

• Protein Length:

  910

• NCBI Gene Symbol:

  RAD54B

• NCBI GB Accession Number:

  RAD54B

• Host or Source:

  Rabbit

• Protein Name:

  DNA repair and recombination protein RAD54B

• Nucleotide Accession Number:

  NM_012415

• Peptide Sequence:

  NSLKPLSMSQLKQWKHFSGDHLNLTDPFLERITENVSFIFQNITTQATGT