TRPC4 Antibody - middle region: Biotin (ARP35256_P050-Biotin)

• Gene Name:

  Transient receptor potential cation channel, subfamily C, member 4

• Gene Aliases:

  TRP4, HTRP4, HTRP-4

• Gene ID:

  7223

• Swiss Prot:

  Q9UBN4

• Accession Number:

  NP_057263

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human TRPC4

• Target:

  TRPC4 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC4 probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. It has also been shown to be calcium-selective. TRPC4 may also be activated by intracellular calcium store depletion.

• Partner Proteins:

  UBC; TRPC4AP; TNFRSF1A; TRPC1; ITCH; SLC9A3R1; TJP1; ITPR2; TRPC5; ITPR3; ITPR1; MX1; TRPC4; TRPC6; TRPC3; HOMER3

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  IHC, WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 86%; Dog: 93%; Guinea Pig: 82%; Horse: 77%; Human: 100%; Mouse: 100%; Pig: 85%; Rabbit: 100%; Rat: 92%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  112kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  977

• NCBI Gene Symbol:

  TRPC4

• Protein Name:

  Short transient receptor potential channel 4

• Nucleotide Accession Number:

  NM_016179