KCNJ4 Antibody - middle region: Biotin (ARP35167_P050-Biotin)

• Gene Name:

  Potassium inwardly-rectifying channel, subfamily J, member 4

• Gene Aliases:

  HIR, HRK1, IRK3, HIRK2, IRK-3, Kir2.3

• Gene ID:

  3761

• Swiss Prot:

  P48050

• Accession Number:

  NP_004972

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog, Guinea Pig, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human KCNJ4

• Target:

  KCNJ4 is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have??een found for this gene. Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neuronsSeveral different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.

• Partner Proteins:

  SNTA1; LIN7B; GNGT2; DLG2; IL16; DLG4; DLG1; KCNJ2; CASK; PRKCD; LIN7C; LIN7A; DMD

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  KCNJ4 is supported by BioGPS gene expression data to be expressed in HEK293T

• Concentration:

  0.5 mg/mL

• Homology:

  Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  49kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  445

• NCBI Gene Symbol:

  KCNJ4

• Protein Name:

  Inward rectifier potassium channel 4

• Nucleotide Accession Number:

  NM_004981