KCNMA1 Antibody - C-terminal: HRP (ARP35092_P050-HRP)

• Gene Name:

  Potassium large conductance calcium-activated channel, subfamily M, alpha member 1

• Gene Aliases:

  SLO, BKTM, SLO1, hSlo, IEG16, LIWAS, MaxiK, PNKD3, SAKCA, mSLO1, CADEDS, KCa1.1, SLO-ALPHA, bA205K10.1

• Gene ID:

  3778

• Swiss Prot:

  Q12791

• Accession Number:

  NP_001014797

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the c terminal region of human KCNMA1

• Target:

  MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits.MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.

• Partner Proteins:

  EED; TBXA2R; KCNMB1; KCNMA1; CAV3; CAV2; CAV1; ACTG2; ACTA2; ALB; CACNA1H; PTK2; MAP1A; GGT1; HMOX2

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 93%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  131kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  1182

• NCBI Gene Symbol:

  KCNMA1

• Protein Name:

  Calcium-activated potassium channel subunit alpha-1

• Nucleotide Accession Number:

  NM_001014797