BTBD1 Antibody - N-terminal region: Biotin (ARP34479_P050-Biotin)

• Gene Name:

  BTB (POZ) domain containing 1

• Gene Aliases:

  C15orf1, NS5ATP8

• Gene ID:

  53339

• Swiss Prot:

  Q9H0C5

• Accession Number:

  NP_079514

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Guinea Pig

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human BTBD1

• Target:

  The C-terminus of BTBD1 binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies.The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms.

• Partner Proteins:

  CUL3; LRR1; FMOD; NEDD8; COPS4; COPS5; COPS3; UBC; TOP1; COPS6; CUL5; SUMO1; TRIM5

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  BTBD1 is supported by BioGPS gene expression data to be expressed in 721_B

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  53kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  482

• NCBI Gene Symbol:

  BTBD1

• Protein Name:

  BTB/POZ domain-containing protein 1

• Nucleotide Accession Number:

  NM_025238