JMJD2C Antibody - C-terminal region: FITC (ARP32974_P050-FITC)

• Gene Name:

  Lysine (K) -specific demethylase 4C

• Gene Aliases:

  GASC1, JHDM3C, JMJD2C, TDRD14C

• Gene ID:

  23081

• Swiss Prot:

  F5H347

• Accession Number:

  NP_001140167

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human JMJD2C

• Target:

  JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.

• Partner Proteins:

  UBC; HIST2H3C; HDAC3; PPARG; HDAC1; H3F3A; HIST1H3A; KDM4C; KDM4A

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  92kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  813

• NCBI Gene Symbol:

  KDM4C

• Protein Name:

  Lysine-specific demethylase 4C Ensembl ENSP00000445427

• Nucleotide Accession Number:

  NM_001146695