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NCGC00244536

CAT: 0804-HY-101799-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101799-01Size:1 mg
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Description
NCGC00244536 is a potent KDM4B inhibitor with an IC50 of 10 nM.
CAS Number
2003260-55-5
Product Name Alternative
KDM4B Inhibitor B3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/NCGC00244536.html
Purity
99.70
Solubility
DMSO : 36.67 mg/mL (ultrasonic)
Smiles
O=C(NCCCC1=CC=CC=C1)C2=CC=CC(C3=CC(O)=C4N=CC=CC4=C3)=C2
Molecular Formula
C25H22N2O2
Molecular Weight
382.45
Precautions
H302, H315, H319, H335
References & Citations
[1]Duan L, et al. KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes. Chem Biol. 2015 Sep 17;22 (9) :1185-96.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM4

Alternative Products

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BA4782-25NCGC00244536
A13025-50NCGC00244536 50mg
A13025-100NCGC00244536 100mg
A13025-10NCGC00244536 10mg
A13025-5NCGC00244536 5mg
A13025-25NCGC00244536 25mg
A13025-1NCGC00244536 1mg
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