APC-Labeled Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3) Star Staining

• Background:

  CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.

• Description:

  APC-Labeled Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a (Clone: OKT3) is produced via conjugation of APC to Anti-Human CD3 Antibody, Mouse IgG2a (OKT3) under optimal conditions with a new generation site-specific technology under Star Staining labeling platform.

• Host:

  HEK293

• Origin Species:

  Mouse

• Target:

  CD3

• Conjugation:

  APC Labeled

• Tag:

  Mouse IgG2a | Mouse Kappa

• Applications:

  Flow Cytometry (Detection the expression of CD3 on Human cells)

• Stability:

  ● -20°C to -70°C for 24 months in lyophilized state; ● -70°C for 12 months after reconstitution; ● 2-8°C for 12 months after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please protect from light and avoid repeated freeze-thaw cycles.

• Format:

  Powder

• Buffer:

  PBS, 0.03% Proclin 300, pH7.4

• Additives:

  Trehalose

• Shipping Conditions:

  RT

• Storage Conditions:

  -20°C, aviod light

• Package Size:

  200tests*1

• Species:

  Mouse

• CAS Number:

  9007-83-4