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MDTF

CAT: 0804-HY-150043A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-150043A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MDTF is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mdtf.html
Purity
95.64
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C([C@H]1CO[C@H](OC1)CN2C(C=CC2=O)=O)OC3=C(C(F)=C(C(F)=C3F)S(=O)(O[Na])=O)F
Molecular Formula
C16H10F4NNaO9S
Molecular Weight
491.30
References & Citations
[1]Dovgan I, et, al. 2- (Maleimidomethyl) -1,3-Dioxanes (MD) : a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation. Sci Rep. 2016 Aug 9;6:30835.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported

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