Lenalidomide-F

Lenalidomide-F

• CAS Number: 2359705-88-5
• UNSPSC Description: Lenalidomide-F is a E3 ligase ligand for LWY713. LWY713 is a PROTAC-class FLT3 degrader (DC50 = 0.64 nM), which selectively induces FLT3 degradation via cereblon and proteasome-dependent pathways[1].
• Target Antigen: Ligands for E3 Ligase
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/lenalidomide-f.html
• Purity: 99.89
• Smiles: O=C(C(N(CC1=C2C=CC=C1F)C2=O)CC3)NC3=O
• Molecular Weight: 262.24
• References & Citations: [1]Liu W et al. Discovery of LWY713 as a potent and selective FLT3 PROTAC degrader with in vivo activity against acute myeloid leukemia. Eur J Med Chem. 2023 Nov 19;264:115974.
• Shipping Conditions: Room Temperature
• Storage Conditions: Store at room temperature 3 years
• Clinical Information: No Development Reported