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Imanixil

CAT: 0804-HY-101529-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101529-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Imanixil (HOE-402 free base) is an orally active LDL receptor (LDLR) inducer. Imanixil can reduce cholesterol levels by inhibiting VLDL-lipid production. Imanixil can delay atherosclerosis profession. Imanixil can be used for the research of cardiovascular disease, such as atherosclerosis[1].
CAS Number
75689-93-9
Product Name Alternative
HOE-402 (free base)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
LDLR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/imanixil.html
Purity
99.29
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CN=C(N2CC(C)(C)NC2=O)N=C1N)NC3=CC=CC(C(F)(F)F)=C3
Molecular Formula
C17H17F3N6O2
Molecular Weight
394.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Draijer R, et al. HOE 402 lowers serum cholesterol levels by reducing VLDL-lipid production, and not by induction of the LDL receptor, and reduces atherosclerosis in wild-type and LDL receptor-deficient mice. Biochem Pharmacol. 2002 May 1;63 (9) :1755-61.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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