Lipid 5

• Description:

  Lipid 5 is an amino lipid that affords efficient mRNA delivery in rodent and primate models. Lipid 5 shows optimal pharmacokinetics and non-toxic side effects[1].

• UNSPSC:

  12352200

• Hazard Statement:

  H225, H350

• Target:

  Liposome

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/lipid-5.html

• Concentration:

  10mM

• Purity:

  99.78

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C (OC (CCCCCCCC) CCCCCCCC) CCCCCCCN (CCO) CCCCCCCC (OCCCCCCCCC) =O

• Molecular Formula:

  C44H87NO5

• Molecular Weight:

  710.17

• Precautions:

  H225, H350

• References & Citations:

  [1]Staci Sabnis, et al. A Novel Amino Lipid Series for mRNA Delivery: Improved Endosomal Escape and Sustained Pharmacology and Safety in Non-human Primates. Mol Ther. 2018 Jun 6;26 (6) :1509-1519.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  2089251-33-0