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(2R) -Flavanomarein

CAT: 0804-HY-N7675ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N7675ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(2R) -Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. (2R) -Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities[1][2].
CAS Number
56389-87-8
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2r-flavanomarein.html
Solubility
10 mM in DMSO
Smiles
OC1=C2C(C(C[C@H](C3=CC(O)=C(C=C3)O)O2)=O)=CC=C1O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO
Molecular Formula
C21H22O11
Molecular Weight
450.39
References & Citations
[1]Nan-Nan Zhang, et al. Flavanomarein inhibits high glucose-stimulated epithelial-mesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase. Sci Rep. 2020 Jan 16;10 (1) :439.|[2]Liang Le, et al. The protective effects of the native flavanone flavanomarein on neuronal cells damaged by 6-OHDA. Phytomedicine. 2019 Feb;53:193-204.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported