Felypressin

• Description:

  Felypressin (PLV-2) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin is widely used in dental procedures[1][2].

• Product Name Alternative:

  PLV-2

• UNSPSC:

  12352209

• Target:

  Vasopressin Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/Felypressin.html

• Purity:

  99.64

• Solubility:

  DMSO : ≥ 10.4 mg/mL|H2O : ≥ 100 mg/mL

• Smiles:

  O=C([C@H](CSSC[C@@H](C(N[C@H](C1=O)CC2=CC=CC=C2)=O)N)NC([C@@H](NC([C@@H](NC([C@](N1)([H])CC3=CC=CC=C3)=O)CCC(N)=O)=O)CC(N)=O)=O)N(CCC4)[C@@H]4C(N[C@@H](CCCCN)C(NCC(N)=O)=O)=O

• Molecular Formula:

  C46H65N13O11S2

• Molecular Weight:

  1040.22

• References & Citations:

  [1]Bronzo AL et al. Felypressin increases blood pressure during dental procedures in hypertensive patients. Arq Bras Cardiol. 2012 Aug;99 (2) :724-31.|[2]Cecanho R et al. Cardiovascular effects of felypressin. Anesth Prog. 2006 Winter;53 (4) :119-25.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  Launched

• Citation 01:

  J Pharm Biomed Anal. 2023 Feb 5:224:115156.|University of Saskatchewan. 2020 Jun 22.|J Pharm Biomed Anal. 2022 Mar 20:211:114518.

• CAS Number:

  56-59-7