Products for Research Use Only

Etodolac (Standard)

CAT: 0804-HY-76251R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-76251R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Etodolac (Standard) is the analytical standard of Etodolac. This product is intended for research and analytical applications. Etodolac (AY-24236) is a non-steroidal anti-inflammatory compound that is a non-selective inhibitor of COX (IC50=53.5 nM)
CAS Number
41340-25-4
Product Name Alternative
AY-24236 (Standard)
UNSPSC
12352005
Hazard Statement
H301-H319-H361
Target
COX; Reference Standards
Type
Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology; Cancer
Assay Protocol
https://www.medchemexpress.com/etodolac-standard.html
Smiles
O=C(O)CC(OCC1)(CC)C2=C1C3=CC=CC(CC)=C3N2
Molecular Formula
C17H21NO3
Molecular Weight
287.35
Precautions
P264-P270-P280-P305+P351+P338-P330-P405-P501
References & Citations
[1]Riendeau D, et al. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. Br J Pharmacol. 1997 May;121 (1) :105-17.|[2]Ito S, Tajima K, Nogawa M et al. Etodolac, a cyclooxygenase-2 inhibitor, attenuates paclitaxel-induced peripheral neuropathy in a mouse model of mechanical allodynia. J Pharmacol Exp Ther. 2012 Jul;342 (1) :53-60.|[3]Yanaoka K, Oka M, Yoshimura N et al. Preventive effects of etodolac, a selective cyclooxygenase-2 inhibitor, on cancer development in extensive metaplastic gastritis, a Helicobacter pylori-negative precancerous lesion. Int J Cancer. 2010 Mar 15;126 (6) :1467-73.|[4]Matsuyama M, Yoshimura R, Hase T et al. Administration of the selective cyclooxygenase (COX) -2 inhibitor etodolac prolongs cardiac allograft survival in a mouse model. Mol Med Report. 2010 Sep-Oct;3 (5) :771-4.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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