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Okanin

CAT: 0804-HY-N6673-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N6673-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Okanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways[1].
CAS Number
484-76-4
UNSPSC
12352005
Target
NF-κB; Toll-like Receptor (TLR)
Type
Natural Products
Related Pathways
Immunology/Inflammation; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/okanin.html
Concentration
10mM
Purity
99.98
Solubility
DMSO : 16.67 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(O)C(O)=C1O)/C=C/C2=CC=C(O)C(O)=C2
Molecular Formula
C15H12O6
Molecular Weight
288.25
References & Citations
[1]Hou Y, et al. Okanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways. Sci Rep. 2017 Apr 3;7:45705.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
RelA/p65; TLR4

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