Lufenuron

• Description:

  Lufenuron is an orally active lipophilic benzoylurea insecticide and a chitin synthesis inhibitor that can used for flea and fish lice control. Lufenuron inhibits moulting of arthropods. Lufenuron induces reproductive toxicity, genotoxic effects and oxidative stresses in pregnant albino rats and their fetuses[1][2][3][4].

• Product Name Alternative:

  TNF Protease Inhibitor 2

• UNSPSC:

  12352005

• Hazard Statement:

  H317, H330, H410

• Target:

  Parasite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/lufenuron.html

• Purity:

  99.57

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  O=C(NC(NC1=CC(Cl)=C(OC(F)(F)C(F)C(F)(F)F)C=C1Cl)=O)C2=C(F)C=CC=C2F

• Molecular Formula:

  C17H8Cl2F8N2O3

• Molecular Weight:

  511.15

• Precautions:

  H317, H330, H410

• References & Citations:

  [1]T C M Brock, et al. Toxicity of Sediment-Bound Lufenuron to Benthic Arthropods in Laboratory Bioassays. Aquat Toxicol. 2018 May;198:118-128.|[2]Cai Wang, et al. Lufenuron Suppresses the Resistance of Formosan Subterranean Termites (Isoptera: Rhinotermitidae) to Entomopathogenic Bacteria. J Econ Entomol. 2013 Aug;106 (4) :1812-8.|[3]Basal WT, et al. Lufenuron induces reproductive toxicity and genotoxic effects in pregnant albino rats and their fetuses. Sci Rep. 2020 Nov 11;10 (1) :19544.|[4]Ghazawy N. Ultrastructural observations on the gonads and neurosecretory cells of schistocerca gregaria after treatment with Lufenuron (CGA-184699) [J]. Journal of Orthoptera Research, 2012, 21 (2) : 141-148.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [103055-07-8]