Thalidomide-N-C3-O-C4-O-C3-OH

Thalidomide-N-C3-O-C4-O-C3-OH

• UNSPSC Description: Thalidomide-N-C3-O-C4-O-C3-OH is a conjugate of E3 ligase and linker for the synthesis of Aster-A PROTAC degrader (HY-D2336)[1].
• Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: Apoptosis;Autophagy;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/thalidomide-n-c3-o-c4-o-c3-oh.html
• Smiles: OCCCOCCCCOCCCNC1=CC(C(N(C2CCC(NC2=O)=O)C3=O)=O)=C3C=C1
• Molecular Weight: 461.51
• References & Citations: [1]Fischer ES, et al. Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide. Nature. 2014 Aug 7;512(7512):49-53.  [Content Brief]
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported