AcBut

• Description :

  AcBut is a cleavable Ozogamicin linker used in the synthesis of Ozogamicin, a agent-linker conjugate for ADC[1].

• Product Name Alternative :

  4- (4-Acetyl-phenoxy) -butyric acid

• UNSPSC :

  12352203

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  ADC Linker

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/acbut-1.html

• Purity :

  98.07

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  O=C(O)CCCOC1=CC=C(C(C)=O)C=C1

• Molecular Formula :

  C12H14O4

• Molecular Weight :

  222.24

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Beck A, et al. Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future. Expert Rev Proteomics. 2019;16 (4) :337-362.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, stored under nitrogen)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• CAS Number :

  [65623-82-7]