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GW701427A

CAT: 0804-HY-160684Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-160684Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GW701427A is a dual inhibitor of Fluc and VEGFR2 with IC50 of 0.12 μM and 603 nM, respectively. GW701427A acts as a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential implications for Fluc reporter assays[1].
CAS Number
433224-56-7
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/gw701427a.html
Solubility
10 mM in DMSO
Smiles
COC(NC1=NC2=C(N1)C=CC(OC3=CC=C(NC(NC4=CC=CC(C(O)=O)=C4)=O)C=C3)=C2)=O
Molecular Formula
C23H19N5O6
Molecular Weight
461.43
References & Citations
[1]Dranchak P, et al. Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays. PLoS One. 2013;8 (3) :e57888.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T86535-01GW701427A

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