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4-Methylcinnamic acid

CAT: 0804-HY-W015399-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W015399-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4-Methylcinnamic acid is a cinnamic acid derivative with antifungal activity. 4-Methylcinnamic acid can overcome the tolerance of glutathione reductase mutants to 4-Methoxycinnamic acid. When 4-Methylcinnamic acid is used in combination with traditional antifungal agents, it can reduce their minimum inhibitory concentrations. 4-Methylcinnamic acid can act as an intervention catalyst to enhance the efficacy of traditional antifungal agents and has application potential in targeting fungal cell wall disruption and controlling drug-resistant fungi[1].
CAS Number
1866-39-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/3-_p-Tolyl_acrylic_acid.html
Concentration
10mM
Purity
99.63
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC=C(C=CC(O)=O)C=C1
Molecular Formula
C10H10O2
Molecular Weight
162.19
Precautions
H302, H315, H319, H335
References & Citations
[1]Kim JH, et, al. Cinnamic Acid Analogs as Intervention Catalysts for Overcoming Antifungal Tolerance. Molecules. 2017 Oct 21;22 (10) :1783.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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