GPRP

• Description :

  GPRP (Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) [1][2].

• Product Name Alternative :

  Gly-Pro-Arg-Pro; Pefa 6003

• UNSPSC :

  12352209

• Target :

  Integrin

• Type :

  Peptides

• Related Pathways :

  Cytoskeleton

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/gprp.html

• Purity :

  99.89

• Solubility :

  DMSO : 66.67 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(O)[C@H]1N(C([C@H](CCCNC(N)=N)NC([C@H]2N(C(CN)=O)CCC2)=O)=O)CCC1

• Molecular Formula :

  C18H31N7O5

• Molecular Weight :

  425.48

• References & Citations :

  [1]Gallistl S, et al. Gly-pro-arg-pro (GPRP) enhances free thrombin. Thromb Res. 1995 Jun 15;78 (6) :547-50.|[2]Hsieh KH, et, al. Fibrin Polymerization. 1. Alkylating peptide inhibitors of fibrin polymerization. J Med Chem. 1981 Mar; 24 (3) : 322-7.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• Citation 01 :

  Res Pract Thromb Haemost. 2025 Sep 24.|Cell Mol Gastroenterol Hepatol. 2021;11 (3) :683-696.|Platelets. 2025 Dec;36 (1) :2517108.

• CAS Number :

  [67869-62-9]