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GPRP

CAT: 0804-HY-P0074-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P0074-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GPRP (Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa) [1][2].
CAS Number
[67869-62-9]
Product Name Alternative
Gly-Pro-Arg-Pro; Pefa 6003
UNSPSC
12352209
Target
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gprp.html
Purity
99.89
Solubility
DMSO : 66.67 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C(O)[C@H]1N(C([C@H](CCCNC(N)=N)NC([C@H]2N(C(CN)=O)CCC2)=O)=O)CCC1
Molecular Formula
C18H31N7O5
Molecular Weight
425.48
References & Citations
[1]Gallistl S, et al. Gly-pro-arg-pro (GPRP) enhances free thrombin. Thromb Res. 1995 Jun 15;78 (6) :547-50.|[2]Hsieh KH, et, al. Fibrin Polymerization. 1. Alkylating peptide inhibitors of fibrin polymerization. J Med Chem. 1981 Mar; 24 (3) : 322-7.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Citation 01
Res Pract Thromb Haemost. 2025 Sep 24.|Cell Mol Gastroenterol Hepatol. 2021;11 (3) :683-696.|Platelets. 2025 Dec;36 (1) :2517108.

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