Polyclonal NG2/Cspg4 Antibody, Rabbit IgG

Polyclonal NG2/Cspg4 Antibody, Rabbit IgG

• Background: Neuronglial antigen 2 (NG2), also known as chondroitin sulphate proteoglycan 4 (CSPG4), is a surface type I transmembrane core proteoglycan that is crucially involved in cell survival, migration and angiogenesis. In the central nervous system, NG2/Cspg4 is expressed in certain glia cells which are sometimes called polydendrocytes or oligodendrocyte precursor cells (OPCs), as well as in mesenchymal stem cells, osteoblasts, melanocytes, smooth muscle cells and macrophages. NG2/Cspg4mediated signaling has been shown to play an important role in the progression of several tumor types including glioblastoma and malignant melanoma. NG2/Cspg4 is also a typical marker for vesselsurrounding pericytes, which contribute to the stabilization of microvessels, the regulation of capillary blood flow and angiogenesis.
  Ampofo E, et al. Cell Mol Biol Lett. 2017;22:4. doi: 10.1186/s1165801700353.
  General Notes: FOR RESEARCH USE ONLY.
• Description: Polyclonal NG2/Cspg4 Antibody, Rabbit IgG is a polyclonal antibody purified from rabbit serum.
  Gene Synonyms: Cspg4, NG2, chondroitin sulfate proteoglycan 4, MCSP, MCSPG, Cspa, Cspg4a; 4732461B14Rik.
• CAS Number: 9007-83-4
• Origin Species: Rabbit
• Target: NG2/Cspg4
• Conjugation: Unconjugated
• Tag: Rabbit IgG
• Stability: Shipped at 20°C. Store at 20°C for 3 years; Shipped at 20°C. Store at 80°C for 5 years._x000D_ _x000D_Please avoid repeated freezethaw cycles.
• Format: Liquid
• Buffer: pH7.4, PBS, 65 mM Tris, 50 Mm Glycine
• Additives: 40% glycerol
• Shipping Conditions: Blue Ice
• Storage Conditions: 20°C