Recombinant Human Wnt3a

• Background:

  Wnt-3a is one of 19 vertebrate members of the Wingless-type MMTV integration site (Wnt) family of highly conserved cysteine-rich secreted glycoproteins important for normal developmental processes.Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube (By similarity) . Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro) .

• Description:

  Recombinant Human Protein Wnt-3a is produced by our Mammalian expression system and the target gene encoding Ser19-Lys352 is expressed with a fusion design at the N-terminus.

• Synonyms:

  MGC119418; MGC119419; MGC119420; protein Wnt-3a; wingless-type MMTV integration site family, member 3A; Wnt3a; Wnt-3a

• UniProt:

  P56704

• Accession Number:

  P56704

• Endotoxin:

  Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.

• Purity:

  Greater than 90% as determined by reducing SDS-PAGE.

• Reconstitution:

  Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

• Molecular Weight:

  105.9 KDa

• Shipping Conditions:

  The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

• Storage Conditions:

  Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Notes:

  Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Observed Molecular Weight:

  100 - 120 KDa, reducing conditions

• Other Product Names:

  MGC119418; MGC119419; MGC119420; protein Wnt-3a; wingless-type MMTV integration site family, member 3A; Wnt3a; Wnt-3a

• CAS Number:

  9000-83-3