(S,R,S)-AHPC-O-CF3-CO-cyclohexene-Bpin

CAT:

804-HY-163950

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UNSPSC Description: (S,R,S)-AHPC-O-CF3-CO-cyclohexene-Bpin is an E3 Ligase Ligand-Linker Conjugate. (S,R,S)-AHPC-O-CF3-CO-cyclohexene-Bpin can be used to synthesize PROTAC SMARCA2/4-degrader-20 (HY-163873)[1].
Target Antigen: E3 Ligase Ligand-Linker Conjugates
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: cancer
Assay Protocol: https://www.medchemexpress.com/s-r-s-ahpc-o-cf3-co-cyclohexene-bpin.html
Smiles: O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=C(OC(F)(F)F)C=C(C3=C(N=CS3)C)C=C2)=O)[C@H](C(C)(C)C)NC(C4CC=C(B5OC(C)(C)C(C)(C)O5)CC4)=O
Molecular Weight: 748.66
References & Citations: [1]Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. USA, US20230072658A1 2020-12-17
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

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HY-163950	(S,R,S)-AHPC-O-CF3-CO-cyclohexene-Bpin
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HY-163954	(S,R,S)-AHPC-Ala-CO-cyclohexene-Bpin
HY-163952	(S,R,S)-AHPC-Ac-CO-cyclohexene-Bpin
HY-159549	(S,R,S)-AHPC-CO-C-Cyclohexene-Bpin
HY-159548	Cyclopropane-(S,R,S)-AHPC-CO-cyclohexene-Bpin
HY-159546	(S,R,S)-AHPC-Me-CO-cyclohexene-Bpin
HY-163937	(S,R,S)-AHPC-O-CF3 -CO-cyclohexane
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