Gavestinel

• UNSPSC Description:

  Gavestinel (GV 150526) is a selective and potent the glycine site of the NMDA receptor antagonist. Gavestinel has neuroprotectant effects[1].

• Target Antigen:

  iGluR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/gavestinel.html

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  O=C(C(N1)=C(/C=C/C(NC2=CC=CC=C2)=O)C3=C1C=C(Cl)C=C3Cl)O

• Molecular Weight:

  375.21

• References & Citations:

  [1]J F Hoke, et al. Pharmacokinetics of a glycine site antagonist (gavestinel) following multiple dosing in patients with acute stroke. Eur J Clin Pharmacol. 2000 Feb-Mar;55(11-12):867-72.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  Phase 2

• CAS Number:

  153436-22-7