Steviolbioside

• Description:

  Steviolbioside is a sweetener and also an important pharmaceutical intermediate. Steviolbioside can inhibit the proliferation of various tumor cells. Steviolbioside has an MIC of 3.8 µg/mL for Mycobacterium tuberculosis. Steviolbioside also has antidiabetic activity. Steviolbioside can be used in the research of tuberculosis, diabetes and tumors such as breast cancer[1][2][3].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H312, H332

• Target:

  Bacterial; Drug Intermediate

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Infection; Metabolic Disease; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/steviolbioside.html

• Purity:

  99.98

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  C[C@]12[C@@]3 ([H]) [C@@] (C4) (CC[C@]1 ([H]) [C@@] (C) (CCC2) C (O) =O) C[C@@] (C4=C) (O[C@@]5 ([H]) [C@@H] ([C@H] ([C@H] (O) [C@@H] (CO) O5) O) O[C@]6 ([H]) O[C@@H] ([C@@H] (O) [C@H] (O) [C@H]6O) CO) CC3

• Molecular Formula:

  C32H50O13

• Molecular Weight:

  642.73

• Precautions:

  H302, H312, H332

• References & Citations:

  [1]Chen JM, et al. Production of a bioactive sweetener steviolbioside via specific hydrolyzing ester linkage of stevioside with a β-galactosidase. Food Chem. 2016 Apr 1;196:155-60.|[2]Myint KZ, et al. Structural dependence of antidiabetic effect of steviol glycosides and their metabolites on streptozotocin-induced diabetic mice. J Sci Food Agric. 2020 Aug;100 (10) :3841-3849.|[3]Kataev VE, et al. [Synthesis and antituberculosis activity of the derivatives of glycoside steviolbioside from the plant Stevia rebaudiana and diterpenoid isosteviol containing hydrazone, hydrazide and pyridinoyl moieties]. Bioorg Khim. 2011 Jul-Aug;37 (4) :542-51.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  41093-60-1