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Orforglipron

CAT: 1596-AR-O09045-01Size: 25 UnitsDry Ice: NoHazardous: No
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CAT#:1596-AR-O09045-01Size:25 Units
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2212020-52-3
Synonyms
3- ((1S,2S) -1- (5- ((S) -2,2-Dimethyltetrahydro-2H-pyran-4-yl) -2- ((S) -3- (3- (4-fluoro-1-methyl-1H-indazol-5-yl) -2-oxo-2,3-dihydro-1H-imidazol-1-yl) -2- (4-fluoro-3,5-dimethylphenyl) -4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine-5-carbonyl) -1H-indol-1-yl) -2-methylcyclopropyl) -1,2,4-oxadiazol-5 (4H) -one
Molecular Formula
C48H48F2N10O5
Molecular Weight
882.97
API Name
Orforglipron

Chemical Information

Orforglipron

Orforglipron is under investigation in clinical trial NCT06010004 (A Long-term Safety Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes).

CAS Number2212020-52-3
PubChem CID137319706
IUPAC Name3-[(1S,2S)-1-[5-[(4S)-2,2-dimethyloxan-4-yl]-2-[(4S)-2-(4-fluoro-3,5-dimethylphenyl)-3-[3-(4-fluoro-1-methylindazol-5-yl)-2-oxoimidazol-1-yl]-4-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carbonyl]indol-1-yl]-2-methylcyclopropyl]-4H-1,2,4-oxadiazol-5-one
Molecular FormulaC48H48F2N10O5
Molecular Weight883.0
XLogP6.8
Topological Polar Surface Area144
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Heavy Atom Count65
Formal Charge0
Complexity1950
SMILES
C[C@H]1C[C@]1(C2=NOC(=O)N2)N3C4=C(C=C(C=C4)[C@H]5CCOC(C5)(C)C)C=C3C(=O)N6CCC7=NN(C(=C7[C@@H]6C)N8C=CN(C8=O)C9=C(C1=C(C=C9)N(N=C1)C)F)C1=CC(=C(C(=C1)C)F)C
InChI
InChI=1S/C48H48F2N10O5/c1-25-18-32(19-26(2)40(25)49)60-42(58-16-15-57(46(58)63)37-11-10-36-33(41(37)50)24-51-55(36)7)39-28(4)56(14-12-34(39)53-60)43(61)38-21-31-20-29(30-13-17-64-47(5,6)23-30)8-9-35(31)59(38)48(22-27(48)3)44-52-45(62)65-54-44/h8-11,15-16,18-21,24,27-28,30H,12-14,17,22-23H2,1-7H3,(H,52,54,62)/t27-,28-,30-,48-/m0/s1
InChIKey
USUWIEBBBWHKNI-KHIFEHGGSA-N
Chemical Structure
2D Structure
2D structure of Orforglipron
CAS: 2212020-52-3
CID: 137319706
Formula: C48H48F2N10O5
MW: 883.0
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight883.0
XLogP36.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Exact Mass882.37772099
Monoisotopic Mass882.37772099
Topological Polar Surface Area144 Ų
Heavy Atom Count65
Formal Charge0
Complexity1950
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
C14503-01Orforglipron
CS-O-58599Orforglipron-d4
CS-O-59412Orforglipron-d3
CS-O-59411Orforglipron-d7
CS-O-59410Orforglipron-d9
CS-O-59409Orforglipron-d10
RM-O493018-01Orforglipron Impurity 18
RM-O493016-01Orforglipron Impurity 16
RM-O493013-01Orforglipron Impurity 13
RM-O493006-01Orforglipron Impurity 6

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