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Recombinant Human Coagulation factor IX (F9), partial

CAT: 0399-CSB-MP007936HU3c9-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0399-CSB-MP007936HU3c9-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Christmas factor; Plasma thromboplastin component
Abbreviation
Recombinant Human F9 protein, partial
Gene Name
F9
UniProt
P00740
Expression Region
93-129aa
Organism
Homo sapiens (Human)
Target Sequence
DGDQCESNPCLNGGSCKDDINSYECWCPFGFEGKNCE
Tag
N-terminal hFc1-tagged
Type
Developed Protein
Source
Mammalian cell
Field of Research
Cardiovascular
Relevance
Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca (2+) ions, phospholipids, and factor VIIIa
Endotoxin
Not test
Purity
Greater than 95% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight
30.7 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Partial

UniProtKB · P00740

Coagulation factor IX

FA9_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00740
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
F9
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.21.22
Processing
Precursor
Secondary accessions
A8K9N4, F2RM36, Q5FBE1, Q5JYJ8
Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Blood coagulationHemostasis

Ligand

CalciumMagnesiumMetal-binding

PTM

Cleavage on pair of basic residuesDisulfide bondGamma-carboxyglutamic acidGlycoproteinHydroxylationPhosphoproteinSulfationZymogen

Disease

Disease variantHemophiliaThrombophilia

Domain

EGF-like domainRepeatSignal

Molecular function

HydrolaseProteaseSerine protease

Cellular component

Secreted

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