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EphB1-IN-1

CAT: 0804-HY-115481-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-115481-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EphB1-IN-1 (Compound 1) is a potent EphB1 inhibitor with IC50s of 3.0, 15 and 220 nM against EphB1G703C, EphB1T697G and EphB1WT, respectively[1].
CAS Number
1980036-18-7
Product Name Alternative
GW876167 hydrochloride; BVT-933 hydrochloride, GW876167; BVT-942
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ephb1-in-1.html
Purity
99.87
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC2=NC=NC(NC3=CC(O)=CC=C3Cl)=C2C=C1)CCl
Molecular Formula
C16H12Cl2N4O2
Molecular Weight
363.20
References & Citations
[1]Kung A, et al. A Chemical-Genetic Approach to Generate Selective Covalent Inhibitors of Protein Kinases. ACS Chem Biol. 2017 Jun 16;12 (6) :1499-1503.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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