Mal-PEG4-Val-Cit-PAB-MMAE

Mal-PEG4-Val-Cit-PAB-MMAE

• UNSPSC Description: Mal-PEG4-Val-Cit-PAB-MMAE is part of a drug-linker conjugate for ADC. Mal-PEG4-Val-Cit-PAB-MMAE contains a degradable ADC linker Mal-PEG4-Val-Cit-PAB (HY-126672) and a potent tubulin inhibitor MMAE (HY-15162)[1].
• Target Antigen: Drug-Linker Conjugates for ADC
• Type: Reference compound
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mal-peg4-val-cit-pab-mmae.html
• Smiles: CN([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)CCC1)=O)C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCN4C(C=CC4=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O
• Molecular Weight: 1450.76
• References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody–drug conjugates[J]. Nature reviews Drug discovery, 2017, 16(5): 315-337.
• Shipping Conditions: Blue Ice
• Clinical Information: No Development Reported