Products for Research Use Only
RegisterLogin

Recombinant Rat Migration Inhibitor Factor

CAT: 0355-AP60496Size: InquireDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0355-AP60496Size:Inquire
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Macrophage migration inhibitory factor (MIF or MMIF), also named as glycosylation-inhibiting factor (GIF), L-dopachrome isomerase, or phenylpyruvate tautomerase, is a protein encoded by the MIF gene. It is released from white blood cells by bacterial antigen stimulation to trigger an acute immune response, or by glucocorticoids to counter-act the inhibitory effects of glucocorticoids on immune system. MIF is a homotrimer of which each subunit contains 115 amino acids. As mentioned above, MIF is involved in the innate immune response to bacterial pathogens and counter-acts the anti-inflammatory activity of glucocorticoids. Furthermore, it also plays a role as mediator in regulating the function of macrophages in host defense and has phenylpyruvate tautomerase and dopachrome tautomerase activity in vitro. Rat MIF is 99 %, 90 %, 89 %, and 89 % a.a. identical to human, murine, porcine and bovine, respectively.
Product Name Alternative
MIF, Glutathione-binding 13 kDa Protein, L-dopachrome Isomerase, L-dopachrome Tautomerase, Phenylpyruvate Tautomerase
Gene ID
81683
UniProt
P30904
Target
MPMFIVNTNV PRASVPEGFL SELTQQLAQA TGKPAQYIAV HVVPDQLMTF SGTSDPCALC SLHSIGKIGG AQNRNYSKLL CGLLSDRLHI SPDRVYINYY DMNAANVGWN GSTFA
Purification
> 97 % by SDS-PAGE and HPLC analyses.
Endotoxin
Less than 1 EU/ug of rRtMIF as determined by LAL method.
Bioactivity
Test in process.
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculated Molecular Weight
Approximately 12.5 kDa, a single non-glycosylated polypeptide chain containing 115 amino acids.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris, pH 8.0, 150 mM NaCl, 3 % trehalose.
Host or Source
Escherichia coli

Related Products

CatalogName
AP60488Recombinant Murine Migration Inhibitor Factor
AP60444Recombinant Human Migration Inhibitor Factor, His, Avi
AP60443Recombinant Human Macrophage Migration Inhibitory Factor
AP85588Macrophage migration inhibitory factor
AP89431Macrophage migration inhibitory factor
AP85626Macrophage migration inhibitory factor
AP78623-01Macrophage migration inhibitory factor
AP85311Macrophage migration inhibitory factor
AP78624Macrophage migration inhibitory factor
EK2140Rat Macrophage migration inhibitory factor ELISA Kit

Alternative Products

CatalogName
P1634-.1Recombinant Murine Migration Inhibitor Factor
GTR19035430-01Recombinant Rat Migration Inhibitor Factor
JOT-PR1093Recombinant Human Migration Inhibitor Factor (rHuMIF)
7-01252Recombinant Human Macrophage Migration Inhibitor Factor
PR1092-01Recombinant Human Migration Inhibitor Factor (rHuMIF)
MBS144617-01Recombinant Rat Macrophage Migration Inhibitor Factor
MBS146204-01Recombinant Mouse Macrophage Migration Inhibitor Factor
RC712-14MIF, Migration Inhibitor Factor, human
CG087-005Human Macrophage Migration Inhibitor Factor
P1660-.01Recombinant Human Migration Inhibitor Factor, His, Avi

Popular Products