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GSK931145

CAT: 0804-HY-111189Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-111189Size:1 Each
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Description
GSK931145 is a glycine transporter 1 (GlyT1) inhibitor with anti-epileptic activity. GSK931145 exhibits a low minimum effective dose in the maximum electrical stimulation threshold test, indicating that it has a significant anti-epileptic effect. GSK931145 is also suitable as a positron emission tomography (PET) radioligand for quantifying the availability of glycine transporters in the living brain[1].
CAS Number
896117-64-9
UNSPSC
12352005
Target
GlyT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gsk931145.html
Smiles
O=C(C1=C(C)C=CC=C1C)NC(C2(CCCC2)N(C)C)C3=CC=CC=C3
Molecular Formula
C23H30N2O
Molecular Weight
350.50
References & Citations
[1]Glycine transporter 1 (GlyT1) inhibitors exhibit anticonvulsant properties in the rat maximal electroshock threshold (MEST) test
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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