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Golocdacimab

CAT: 0804-HY-P99646-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99646-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Golocdacimab (MEDI6570) is a fully human anti-LOX-1 monoclonal antibody. Golocdacimab (MEDI6570) has the potential to be used in the treatment of type 2 diabetes[1].
CAS Number
2418540-63-1
Product Name Alternative
MEDI6570
UNSPSC
12352203
Target
LOX-1
Type
Inhibitory Antibodies
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/golocdacimab.html
Purity
99.11
Solubility
10 mM in DMSO
Smiles
[Golocdacimab]
Molecular Weight
(146.64 kDa)
References & Citations
[1]Vavere AL, et al. Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1 Inhibition in Type 2 Diabetes: Phase 1 Results. J Am Heart Assoc. 2023 Feb 7;12 (3) :e027540.|[2]Varma V, et al. Identification of Response Biomarkers and Signaling Pathways Associated With the LOX-1 Blockade by MEDI6570 in Type 2 Diabetes[J]. Circulation, 2022, 146 (Suppl_1) : A11971-A11971.|[3]Canoneo C N. Contributions of Macrophages in the Disease Pathology of Myocardial Infarction and Atherosclerosis: A Literature Review[J]. Undergraduate Research in Natural and Clinical Science and Technology Journal, 2024, 8: 1-10.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2

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