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Z433927330

CAT: 0804-HY-126074-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126074-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC50s of ~0.2 µM, ~0.7 µM and ~1.1 µM for mAQP7, mAQP3 and mAQP9, respectively[1].
CAS Number
1005883-72-6
UNSPSC
12352005
Target
Aquaporin
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/z433927330.html
Purity
98.11
Solubility
DMSO : ≥ 280 mg/mL
Smiles
O=C(OCC)C1=CC=C(NC(NCC2=CC=C(N3N=CC=C3)C=C2)=O)C=C1
Molecular Formula
C20H20N4O3
Molecular Weight
364.40
References & Citations
[1]Z433927330, et al. Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors. J Biol Chem. 2019 May 3;294 (18) :7377-7387.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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