Scopine

• Description:

  Scopine is a metabolite of Scopolamine (HY-N0296) and brain-targeting compound. Scopine significantly increases the brain exposure of Chlorambucil (HY-13593) and enhances its anti-glioma activity. Scopine can be used in targeted therapy research for brain gliomas[1].

• Product Name Alternative:

  6,7-Epoxytropine

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Drug Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Cancer; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/scopine.html

• Purity:

  98.0

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  [H][C@@]12[C@]3([H])[C@@]([H])(O3)[C@@](C[C@H](O)C2)([H])N1C

• Molecular Formula:

  C8H13NO2

• Molecular Weight:

  155.19

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Wang X, et al. Scopine as a novel brain-targeting moiety enhances the brain uptake of chlorambucil. Bioconjug Chem. 2014 Nov 19;25 (11) :2046-54.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  α adrenergic receptor

• Citation 01:

  Molecules. 2025 Oct 23;30 (21) :4170.|Anal Bioanal Chem. 2025 Jun;417 (14) :3169-3176.

• CAS Number:

  [498-45-3]