Products for Research Use Only
RegisterLogin

TMC353121

CAT: 0804-HY-11097Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-11097Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
TMC353121 is a potent respiratory syncytial virus (RSV) fusion inhibitor with pEC50 of 9.9.
CAS Number
857066-90-1
UNSPSC
12352005
Target
RSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/TMC353121.html
Purity
97.63
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=CC=C(C)N=C1CN2C3=CC(CNC4=CC(C)=CC=C4CCCO)=CC=C3N=C2NCCCN5CCOCC5
Molecular Formula
C32H42N6O3
Molecular Weight
558.71
References & Citations
[1]Bonfanti JF, et al. Selection of a respiratory syncytial virus fusion inhibitor clinical candidate. 2. Discovery of a morpholinopropylaminobenzimidazole derivative (TMC353121) . J Med Chem. 2008 Feb 28;51 (4) :875-96.|[2]Rouan MC, et al. Pharmacokinetics-pharmacodynamics of a respiratory syncytial virus fusion inhibitor in the cotton rat model. Antimicrob Agents Chemother. 2010 Nov;54 (11) :4534-9.|[3]Olszewska W, et al. Antiviral and lung protective activity of a novel respiratory syncytial virus fusion inhibitor in a mouse model. Eur Respir J. 2011 Aug;38 (2) :401-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
C04156TMC353121
A11585-5TMC353121 5mg
A11585-25TMC353121 25mg
A11585-2TMC353121 2mg
A11585-50TMC353121 50mg
A11585-10TMC353121 10mg

Popular Products