Dot1L-IN-4

Dot1L-IN-4

• CAS Number: 2565705-02-2
• UNSPSC Description: Dot1L-IN-4 is a potent disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor with an IC50 SPA DOT1L of 0.11 nM[1].
• Target Antigen: Histone Methyltransferase
• Type: Reference compound
• Related Pathways: Epigenetics
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dot1l-in-4.html
• Smiles: O=S(C1=CC=C(N[C@H](C2=NC=CC=C2Cl)C3=C4OC(F)(F)OC4=CC=C3)C(NC5=NC(OC)=NC(N6CCNCC6)=N5)=C1)(C)=O
• Molecular Weight: 661.08
• References & Citations: [1]Frédéric Stauffer, et al. New Potent DOT1L Inhibitors for in Vivo Evaluation in Mouse. ACS Med. Chem. Lett. 2019, 10, 12, 1655-1660.
• Shipping Conditions: Room Temperature