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Recombinant Beta Secretase 2 (BACE2)

CAT: 0338-TRV-030128-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0338-TRV-030128-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9000-83-3
Product Name Alternative
AEPLC; ALP56; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP; Beta-Site APP Cleaving Enzyme 2; Aspartic-like protease 56 kDa; Aspartyl protease 1; Down region aspartic protease; Memapsin-1
Synonyms
Beta Secretase 2
UniProt
Q6IE75
Expression System
Prokaryotic expression
Host
E. coli
Tag
N-terminal His and GST Tag
Source
Prokaryotic expression
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
Field of Research
Enzyme & Kinase; Neuro science
Endotoxin
<1.0EU per 1μg (determined by the LAL method)
Purity
> 95%
Form
Freeze-dried powder
Buffer
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Calculated Molecular Weight
60.9kDa
Observed Molecular Weight
59kDa
Fragment
Gly242~Val502 (Accession # Q6IE75)
Isoelectric Point
5.5
Subcellular Location
Membrane; Single-pass type I membrane protein. Golgi apparatus. Endoplasmic reticulum. Endosome. Cell surfac
Product Name Synonym
Beta Secretase 2
Host or Source
E.coli
Organism Species
Rattus norvegicus (Rat)

UniProtKB · Q6IE75

Beta-secretase 2

BACE2_RAT · Rattus norvegicus

View on UniProt ↗
Primary accession
Q6IE75
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Bace2
Protein existence
2: Evidence at transcript level
Organism
Rattus norvegicus (Rat)
Taxonomy ID
10116
Alternative names
—
EC number
3.4.23.45
Processing
Precursor
Secondary accessions
B2GVB0
Protein keywords

Molecular function

Aspartyl proteaseHydrolaseProtease

PTM

Autocatalytic cleavageDisulfide bondGlycoproteinZymogen

Cellular component

Cell membraneEndoplasmic reticulumEndosomeGolgi apparatusMembrane

Technical term

Reference proteome

Domain

SignalTransmembraneTransmembrane helix

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