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Recombinant Na-Cl Cotransporter (NCCT)

CAT: 0338-TRV-038110-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0338-TRV-038110-01Size:10 µg
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CAS Number
9000-83-3
Product Name Alternative
SLC12A3; TSC; NCC; Solute Carrier Family 12 Member 3, Sodium/Chloride Transporters; Thiazide-sensitive sodium-chloride cotransporter; Na-Cl symporter
Synonyms
Na-Cl Cotransporter
UniProt
P55017
Expression System
Prokaryotic expression
Host
E. coli
Tag
N-terminal His Tag
Source
Prokaryotic expression
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
Field of Research
Signal transduction
Endotoxin
<1.0EU per 1μg (determined by the LAL method)
Purity
> 90%
Form
Freeze-dried powder
Buffer
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Calculated Molecular Weight
19.6kDa
Observed Molecular Weight
22kDa
Fragment
Lys867~Val1024
Isoelectric Point
9.3
Subcellular Location
Membrane
Product Name Synonym
Na-Cl Cotransporter
Host or Source
E.coli
Organism Species
Homo sapiens (Human)

UniProtKB · P55017

Solute carrier family 12 member 3

S12A3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P55017
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC12A3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8MSJ2, C9JNN9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingChlorideNucleotide-bindingSodium

Cellular component

Cell membraneMembrane

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Biological process

Ion transportSodium transportSymportTransport

Domain

TransmembraneTransmembrane helix