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Recombinant Sirtuin 1 (SIRT1)

CAT: 0338-TRV-039378-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0338-TRV-039378-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9000-83-3
Product Name Alternative
SIR2L1; Silent Mating Type Information Regulation 2 Homolog 1; NAD-Dependent Deacetylase Sirtuin-1; SIR2-like protein 1; SirtT1 75 kDa fragment
Synonyms
Sirtuin 1
UniProt
Q96EB6
Expression System
Prokaryotic expression
Host
E. coli
Tag
N-terminal His Tag
Source
Prokaryotic expression
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
Field of Research
Endocrinology
Endotoxin
<1.0EU per 1μg (determined by the LAL method)
Purity
> 95%
Form
Freeze-dried powder
Buffer
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Calculated Molecular Weight
30.3kDa
Observed Molecular Weight
19&28kDa
Fragment
Glu244~Ala498
Isoelectric Point
5.9
Subcellular Location
Nucleus
Product Name Synonym
Sirtuin 1
Host or Source
E.coli
Organism Species
Homo sapiens (Human)

UniProtKB · Q96EB6

NAD-dependent protein deacetylase sirtuin-1

SIR1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96EB6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SIRT1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
hSIRT1
EC number
2.3.1.286
Processing
—
Secondary accessions
Q2XNF6, Q5JVQ0, Q9GZR9, Q9Y6F0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoproteinS-nitrosylationUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisBiological rhythmsDifferentiationHost-virus interactionMyogenesisTranscriptionTranscription regulation

Cellular component

CytoplasmMitochondrionNucleus

Molecular function

Developmental proteinTransferase

Ligand

Metal-bindingNADZinc

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