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Recombinant Perforin 1 (PRF1)

CAT: 0338-TRV-036045-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0338-TRV-036045-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9000-83-3
Product Name Alternative
FLH2; HPLH2; P1; PFP; Pore Forming Protein; Cytolysin; Lymphocyte pore-forming protein
Synonyms
Perforin 1
UniProt
P14222
Expression System
Prokaryotic expression
Host
E. coli
Tag
N-terminal His and GST Tag
Source
Prokaryotic expression
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
Field of Research
Immune molecule
Endotoxin
<1.0EU per 1μg (determined by the LAL method)
Purity
> 95%
Form
Freeze-dried powder
Buffer
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Calculated Molecular Weight
63.4kDa
Observed Molecular Weight
62kDa
Fragment
Lys32~Phe316
Isoelectric Point
7
Subcellular Location
Membrane, Secreted, Cytoplasm, Endosome
Product Name Synonym
Perforin 1
Host or Source
E.coli
Organism Species
Homo sapiens (Human)

UniProtKB · P14222

Perforin-1

PERF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P14222
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRF1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
P1
EC number
—
Processing
Precursor
Secondary accessions
B2R6X4, Q59F57, Q86WX7
Protein keywords

Ligand

CalciumMetal-binding

Cellular component

Cell membraneEndosomeLysosomeMembraneSecreted

Biological process

Cytolysis

Disease

Disease variantFamilial hemophagocytic lymphohistiocytosis

PTM

Disulfide bondGlycoprotein

Domain

EGF-like domainSignalTransmembraneTransmembrane beta strand

Technical term

Proteomics identificationReference proteome

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