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Recombinant Caspase 8 (CASP8)

CAT: 0338-TRV-036980-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0338-TRV-036980-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9000-83-3
Product Name Alternative
CAP4; FLICE; MACH; MCH5; Cysteinyl Aspartate Specific Proteinases 8; Apoptotic cysteine protease; FADD-homologous ICE/ced-3-like protease; MORT1-associated ced-3 homolog
Synonyms
Caspase 8
UniProt
Q14790
Expression System
Prokaryotic expression
Host
E. coli
Tag
N-terminal His Tag
Source
Prokaryotic expression
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
Field of Research
Signal transduction; Enzyme & Kinase; Apoptosis; Tumor immunity; Neuro science
Endotoxin
<1.0EU per 1μg (determined by the LAL method)
Purity
> 90%
Form
Freeze-dried powder
Buffer
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Calculated Molecular Weight
22.8kDa
Observed Molecular Weight
25kDa
Fragment
Ser217~Asp384
Isoelectric Point
6
Subcellular Location
Cytoplasm
Product Name Synonym
Caspase 8
Host or Source
E.coli
Organism Species
Homo sapiens (Human)

UniProtKB · Q14790

Caspase-8

CASP8_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14790
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CASP8
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CASP-8
EC number
3.4.22.61
Processing
Precursor
Secondary accessions
O14676, Q14791, Q14792, Q14793, Q14794, Q14795, Q14796, Q15780, Q15806, Q53TT5, Q8TDI1, Q8TDI2, Q8TDI3, Q8TDI4, Q8TDI5, Q96T22, Q9C0K4, Q9UQ81
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinZymogen

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisHost-virus interaction

Cellular component

Cell projectionCytoplasmNucleus

Disease

Disease variant

Molecular function

HydrolaseProteaseThiol protease

Domain

Repeat