Recombinant Coagulation Factor II (F2)

CAT: 0338-TRV-026510-01Size: 10 µgDry Ice: NoHazardous: No

1 / 1

CAT#:0338-TRV-026510-01Size:10 µg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

9000-83-3

Product Name Alternative

FII; TM; PT; Thrombin; Prothrombin; Pro-Thrombin; Activation peptide fragment 1; Activation peptide fragment 2

Synonyms

Coagulation Factor II

UniProt

P00734

Expression System

Prokaryotic expression

Host

E. coli

Tag

N-terminal His Tag

Source

Prokaryotic expression

Applications

Positive Control; Immunogen; SDS-PAGE; WB.

Field of Research

Signal transduction; Hematology

Endotoxin

<1.0EU per 1μg (determined by the LAL method)

Purity

> 80%

Form

Freeze-dried powder

Buffer

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Calculated Molecular Weight

20.9kDa

Observed Molecular Weight

21&23kDa

Fragment

Ala44~Arg198

Isoelectric Point

Subcellular Location

Secreted

Product Name Synonym

Coagulation Factor II

Host or Source

E.coli

Organism Species

Homo sapiens (Human)

UniProtKB · P00734

Prothrombin

THRB_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P00734
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: F2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.4.21.5
Processing: Precursor
Secondary accessions: B2R7F7, B4E1A7, Q4QZ40, Q53H04, Q53H06, Q69EZ7, Q7Z7P3, Q9UCA1

Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Biological process

Acute phaseBlood coagulationHemostasis

Ligand

Calcium

PTM

Cleavage on pair of basic residuesDisulfide bondGamma-carboxyglutamic acidGlycoproteinZymogen

Disease

Disease variantThrombophilia

Molecular function

HydrolaseProteaseSerine protease

Domain

KringleRepeatSignal

Cellular component