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NSC666715

CAT: 0804-HY-120105Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120105Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NSC666715 is a strand-displacement activity of DNA polymerase inhibitor. NSC666715 potentiates Temozolomide -induced DNA damage, cell senescence and apoptosis. NSC666715 can be used for study colorectal cancer[1].
CAS Number
170747-33-8
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsc666715.html
Smiles
O=S(C1=CC(C)=C(Cl)C=C1S)(NC2=NN=C(NC3=CC=C(Cl)C=C3)N2)=O
Molecular Formula
C15H13Cl2N5O2S2
Molecular Weight
430.33
References & Citations
[1]Jaiswal AS, et al. NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase β and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer Cells. PLoS One. 2015;10 (5) :e0123808. Published 2015 May 1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
T24555-01NSC666715

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