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Ipilimumab ELISA Kit

CAT: 1358-DB651018Size: 96 TestsDry Ice: NoHazardous: No
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CAT#:1358-DB651018Size:96 Tests
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Ipilimumab is a fully human IgG1 kappa antibody that binds to CTLA-4 (cytotoxic T lymphocyte associated antigen 4), a molecule on T cells that is indicated for unresectable or metastatic melanoma. The absence or presence of CTLA-4 can augment or suppress the immune system's T-cell response in fighting disease. Ipilimumab is designed to block the activity of CTLA-4, thereby sustaining an active immune response in its attack on cancer cells. The proposed mechanism of action is indirect, and may be through T-cell - mediated anti-tumor immune responses.
Specifications
Ipilimumab
Product Name Alternative
BMS-734016, MDX-010, MDX-CTLA-4, CAS: 477202-00-9
Detection Method
Colorimetric
Assay Type
Quantitative
Sample Type
Plasma, Serum
Detection Range
0.31-5 μg/mL
Recovery
80-120%
Sensitivity
0.156 μg/ml
Shipping Conditions
2-8 °C
Storage Conditions
The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Notes
For Research Use Only.

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